成人色图库,粗喘娇吟1V1军婚H,欧美午夜精品久久久,国产欧美日韩A片免费软件,成人欧美一区二区三区黑人免费,欧美日韩一区二区三区在线,国产真人做爰视频免费,久久精品天天爽夜夜爽,国产对白精品刺激一区二区,日本久久久久久级做爰片

發表期刊：Biomedical Chromatography

發表時間：2025

Abstract:

Xiaoqinglong decoction (XQLT), a classical traditional Chinese medicine (TCM) formula, has demonstrated significant efficacy in the treatment of asthma. However, existing quality evaluation methods for this compound lack direct correlation with its therapeutic effects. This study aims to identify the chemical constituents of XQLT and establish quality markers (Q-Markers) associated with its efficacy in asthma treatment. UHPLC-Q-Exactive Orbitrap MS, assisted by comprehensive database analysis, was employed for the total component analysis of XQLT. This approach facilitated the evaluation of Q-Markers based on the principles of component testability, ingredient specificity, and formula compatibility environment. The identified compounds were subsequently subjected to network pharmacology, bioinformatics, and molecular docking analyses to further assess their component validity and traceability. A total of 143 chemical components were identified, including flavonoids, terpenoids, and steroids, organic acids, phenylpropanoids, alkaloids, sugars and derivatives, and other components. Seven key compounds, 18β-glycyrrhetinic acid, liquiritin, formononetin, liquiritigenin, 6-gingerol, neoisostegane, and 2-Methoxycinnamaldehyde, were proposed as potential Q-Markers for XQLT in asthma treatment. The establishment of Q-Markers not only enhances the understanding of XQLT's therapeutic mechanisms but also provides a scientific basis for its pharmacodynamic material foundation and quality control.

https://doi.org/10.1002/bmc.70182Digital Object Identifier